Brain mechanisms of pain affect and pain modulation

被引：438

作者：

Rainville, P ^{[1
]}

机构：

[1] Univ Montreal, Fac Med Dent, Dept Stomatol, Montreal, PQ H3C 3J7, Canada

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2002年 / 12卷 / 02期

关键词：

D O I：

10.1016/S0959-4388(02)00313-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent animal studies reveal ascending nociceptive and descending modulatory pathways that may contribute to the affective-motivational aspects of pain and play a critical role in the modulation of pain. In humans, a reliable pattern of cerebral activity occurs during the subjective experience of pain. Activity within the anterior cingulate cortex and possibly in other classical limbic structures, appears to be closely related to the subjective experience of pain unpleasantness and may reflect the regulation of endogenous mechanisms of pain modulation.

引用

页码：195 / 204

页数：10

共 95 条

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