Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases

被引：27

作者：

Thirion, Muriel ^{[1
]}

Ochiya, Takahiro ^{[1
]}

机构：

[1] Natl Canc Ctr, Res Inst, Div Mol & Cellular Med, Chuo Ku, Tokyo 1040045, Japan

来源：

VIRUSES-BASEL | 2013年 / 5卷 / 11期

关键词：

hepatitis B virus; microRNA; hepatocellular carcinoma; HEPATOCELLULAR-CARCINOMA; LIVER-CANCER; EPIGENETIC REGULATION; VIRAL REPLICATION; RNA ABUNDANCE; CELLULAR-DNA; X PROTEIN; EXPRESSION; TARGETS; GENE;

D O I：

10.3390/v5112690

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.

引用

页码：2690 / 2703

页数：14

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