The functions of animal microRNAs

被引：9351

作者：

Ambros, V ^{[1
]}

机构：

[1] Dartmouth Coll Sch Med, Dept Genet, Hanover, NH 03755 USA

来源：

NATURE | 2004年 / 431卷 / 7006期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nature02871

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and many of these are phylogenetically conserved. With miRNA roles identified in developmental timing, cell death, cell proliferation, haematopoiesis and patterning of the nervous system, evidence is mounting that animal miRNAs are more numerous, and their regulatory impact more pervasive, than was previously suspected.

引用

页码：350 / 355

页数：6

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