Effect of functional catechol-O-methyltransferase Val158Met polymorphism on physical aggression

被引：23

作者：

Kulikova, M. A. ^{[1
]}

Maluchenko, N. V.

Timofeeva, M. A.

Shlepzova, V. A.

Schegolkova, J. V.

Sysoeva, O. V. ^{[2
]}

Ivanitsky, A. M. ^{[2
]}

Tonevitsky, A. G.

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Moscow 117234, Russia

[2] Russian Acad Sci, Inst Higher Nervous Act & Neurophysiol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2008年 / 145卷 / 01期

关键词：

catechol-O-methyltransferase; Val158Met polymorphism; physical aggressiveness;

D O I：

10.1007/s10517-008-0006-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Genetic and psychological analysis of the relationships between catechol-O-methyltransferase Val158Met polymorphism and various types of aggressiveness was performed in 114 women. Dispersion analysis revealed significant association of ValVal genotype with elevated physical aggression.

引用

页码：62 / 64

页数：3

共 15 条

[11] EFFECT OF 6-HYDROXYDOPAMINE-INDUCED LESIONS OF A10 DOPAMINERGIC-NEURONS ON AGGRESSIVE-BEHAVIOR IN RATS [J].

PUCILOWSKI, O ;

KOSTOWSKI, W ;

BIDZINSKI, A ;

HAUPTMANN, M .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1982, 16 (04) :547-551

[12] Association of the functional catechol-O-methyltransferase VALI58MET polymorphism with the personality trait of extraversion [J].

Reuter, M ;

Hennig, J .

NEUROREPORT, 2005, 16 (10) :1135-1138

[13] Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex [J].

Smolka, MN ;

Schumann, G ;

Wrase, J ;

Grüsser, SM ;

Flor, H ;

Mann, K ;

Braus, DF ;

Goldman, D ;

Büchel, C ;

Heinz, A .

JOURNAL OF NEUROSCIENCE, 2005, 25 (04) :836-842

[14] Catecholamines and aggression - The role of COMT and MAO polymorphisms [J].

Volavka, J ;

Bilder, R ;

Nolan, K .

YOUTH VIOLENCE: SCIENTIFIC APPROACHES TO PREVENTION, 2004, 1036 :393-398

[15] COMT genotype predicts BOLD signal and noise characteristics in prefrontal circuits [J].

Winterer, Georg ;

Musso, Francesco ;

Vucurevic, Goran ;

Stoeter, Peter ;

Konrad, Andreas ;

Seker, Berna ;

Gallinat, Juergen ;

Dahmen, Norbert ;

Weinberger, Daniel R. .

NEUROIMAGE, 2006, 32 (04) :1722-1732

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