Polyurethane-covered metal stent for management of distal malignant biliary obstruction

被引:139
作者
Isayama, H
Komatsu, Y
Tsujino, T
Yoshida, H
Tada, M
Shiratori, Y
Kawabe, T
Omata, M
机构
[1] Univ Tokyo, Fac Med, Dept Gastroenterol, Bunkyo Ku, Tokyo 1138655, Japan
[2] Univ Tokyo, Fac Med, Dept Endoscopy & Endoscop Surg, Tokyo 1138655, Japan
关键词
D O I
10.1067/mge.2002.121876
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: The efficacy of polyurethane-covered metal expandable stents for treatment of neoplastic distal biliary obstruction was analyzed. Methods: Twenty-one patients with unresectable malignant tumors involving the mid to distal bile duct who were seen with obstructive jaundice were consecutively enrolled. Eighteen patients underwent endoscopic implantation of a polyurethane-covered metal stent and 3 patients underwent transhepatic insertion because of duodenal obstruction. The stent patency, complications, and patient survival were analyzed. Results: Effective biliary decompression was achieved in all patients. Adverse events were minor: mild pancreatitis (1) and cholecystitis (2) occurred within 7 days of stent insertion. Mean survival and stent patency were 233 days and 206 days, respectively. Stent occlusion occurred in 3 patients (14%) after a mean of 188 days. Tumor ingrowth through the stent mesh was not observed. However, 2 stents were occluded by tumor overgrowth and I by compacted alimentary debris. Conclusions: A polyurethane membrane may prevent tumor ingrowth and reduce the occlusion rate for expandable metal stents implanted in patients with malignant obstruction of the distal bile duct.
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页码:366 / 370
页数:5
相关论文
共 31 条
[31]   Covered self-expanding transhepatic biliary stents: Clinical pilot study [J].
Thurnher, SA ;
Lammer, J ;
Thurnher, MM ;
Winkelbauer, F ;
Graf, O ;
Wildling, R .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 1996, 19 (01) :10-14