Nickel essentiality, toxicity, and carcinogenicity

被引：909

作者：

Denkhaus, E

Salnikow, K

机构：

[1] Univ Duisburg Gesamthsch, Dept Instrumental Anal Chem, D-47057 Duisburg, Germany

[2] New York Univ, Sch med, Nelson Inst Environm Med, New York, NY 10016 USA

[3] New York Univ, Sch med, Kaplan Comprehens Canc Ctr, New York, NY 10016 USA

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2002年 / 42卷 / 01期

关键词：

nickel toxicity; nickel carcinogenicity; nickel essentiality;

D O I：

10.1016/S1040-8428(01)00214-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The increasing utilization of heavy metals in modern industries leads to an increase in the environmental burden. Nickel represents a good example of a metal whose use is widening in modern technologies. As the result of accelerated consumption of nickel-containing products nickel compounds are released to the environment at all stages of production and utilization. Their accumulation in the environment may represent a serious hazard to human health. Among the known health related effects of nickel are skin allergies, lung fibrosis, variable degrees of kidney and cardiovascular system poisoning and stimulation of neoplastic transformation. The mechanism of the latter effect is not known and is the subject of detailed investigation. This review provides an analysis of the current state in the field. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：35 / 56

页数：22

共 247 条

[31]

CHRISTIE NT, 1992, NICKEL HUMAN HLTH CU, P305

[32]

CONWAY K, 1989, CANCER RES, V49, P6032

[33] TOXICITY AND CARCINOGENICITY OF NICKEL COMPOUNDS [J].

COOGAN, TP ;

LATTA, DM ;

SNOW, ET ;

COSTA, M .

CRC CRITICAL REVIEWS IN TOXICOLOGY, 1989, 19 (04) :341-384

[34] SAMPLE COLLECTION GUIDELINES FOR TRACE-ELEMENTS IN BLOOD AND URINE [J].

CORNELIS, R ;

HEINZOW, B ;

HERBER, RFM ;

CHRISTENSEN, JM ;

PAULSEN, OM ;

SABBIONI, E ;

TEMPLETON, DM ;

THOMASSEN, Y ;

VAHTER, M ;

VESTERBERG, O .

PURE AND APPLIED CHEMISTRY, 1995, 67 (8-9) :1575-1608

[35]

COSTA M, 1979, CANCER RES, V39, P3591

[36] FACTORS INFLUENCING THE PHAGOCYTOSIS, NEOPLASTIC TRANSFORMATION, AND CYTO-TOXICITY OF PARTICULATE NICKEL COMPOUNDS IN TISSUE-CULTURE SYSTEMS [J].

COSTA, M ;

ABBRACCHIO, MP ;

SIMMONSHANSEN, J .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1981, 60 (02) :313-323

[37]

COSTA M, 1981, CANCER RES, V41, P2868

[38] CARCINOGENIC ACTIVITY OF PARTICULATE NICKEL COMPOUNDS IS PROPORTIONAL TO THEIR CELLULAR UPTAKE [J].

COSTA, M ;

MOLLENHAUER, HH .

SCIENCE, 1980, 209 (4455) :515-517

[39]

COTTON FA, 1980, ADV INORG CHEM, P783

[40]

Coyle C.L, 1988, BIOINORGANIC CHEM NI, P1

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