Drug Therapy for Atrial Fibrillation

被引:5
作者
Conway, Emily L. [1 ]
Musco, Simone [1 ]
Kowey, Peter R. [1 ,2 ]
机构
[1] Lankenau Hosp, Div Cardiovasc Dis, Main Line Heart Ctr, Wynnewood, PA 19096 USA
[2] Thomas Jefferson Univ, Philadelphia, PA 19107 USA
关键词
Atrial fibrillation; Pharmacologic therapy; Rhythm control; Prevention; MAINTAINING SINUS RHYTHM; ANGIOTENSIN-II ANTAGONIST; CONGESTIVE-HEART-FAILURE; N-3; FATTY-ACIDS; ANTIARRHYTHMIC-DRUGS; MYOCARDIAL-INFARCTION; RECEPTOR ANTAGONIST; SUSTAINED-RELEASE; RAPID CONVERSION; CONTROLLED-TRIAL;
D O I
10.1016/j.ccl.2008.10.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atrial fibrillation is the most frequently diagnosed arrhythmia. Prevalence increases with age, and the overall incidence is expected to increase as the population continues to age. Choice of pharmacologic therapy for atrial fibrillation depends on whether or not the goal of treatment is maintaining sinus rhythm or tolerating atrial fibrillation with adequate control of ventricular rates. Many new antiarrhythmic drugs are currently being tested in clinical trials. Drugs that target remodeling and inflammation have shown potential in prevention of atrial fibrillation, or as adjunctive therapy.
引用
收藏
页码:109 / +
页数:16
相关论文
共 107 条
[1]   Outpatient treatment of recent-onset atrial fibrillation with the "pill-in-the-pocket'' approach [J].
Alboni, P ;
Botto, GL ;
Baldi, N ;
Luzi, M ;
Russo, V ;
Gianfranchi, L ;
Marchi, P ;
Calzolari, M ;
Solano, A ;
Baroffio, R ;
Gaggioli, G .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (23) :2384-2391
[2]   Statin use is associated with a reduction in atrial fibrillation after noncardiac thoracic surgery independent of C-reactive protein [J].
Amar, D ;
Zhang, H ;
Heerdt, PM ;
Park, B ;
Fleisher, M ;
Thaler, HT .
CHEST, 2005, 128 (05) :3421-3427
[3]   Meta-analysis: Inhibition of renin-angiotensin system prevents new-onset atrial fibrillation [J].
Anand, Kishlay ;
Mooss, Aryan N. ;
Hee, Tom T. ;
Mohiuddin, Syed M. .
AMERICAN HEART JOURNAL, 2006, 152 (02) :217-222
[4]  
[Anonymous], 2006, J AM COLL CARDIOL
[5]  
Beatch GN, 2003, CIRCULATION, V108, P85
[6]  
BEATCH GN, 2002, PACING CLIN ELECTROP, V25, P698
[7]  
Biscione Francesco, 2005, Ital Heart J Suppl, V6, P53
[8]   Early class III drugs for the treatment of atrial fibrillation -: Efficacy and atrial selectivity of AVE0118 in remodeled atria of the goat [J].
Blaauw, Y ;
Gögelein, H ;
Tieleman, RG ;
van Hunnik, A ;
Schotten, U ;
Allessie, MA .
CIRCULATION, 2004, 110 (13) :1717-1724
[9]   Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: from pathophysiology to clinical trials [J].
Boos, CJ ;
Lip, GYH .
JOURNAL OF HUMAN HYPERTENSION, 2005, 19 (11) :855-859
[10]   Pharmacological cardioversion of atrial fibrillation - Current management and treatment options [J].
Boriani, G ;
Diemberger, I ;
Biffi, M ;
Martignani, C ;
Branzi, A .
DRUGS, 2004, 64 (24) :2741-2762