Prognostic factors in breast cancer: Current and new predictors of metastasis

被引：179

作者：

Hayes, DF

Isaacs, C

Stearns, V

机构：

[1] Univ Michigan, Ctr Comprehens Canc, Breast Oncol Program, Ann Arbor, MI 48109 USA

[2] Georgetown Univ, Vincent T Lombardi Canc Res Ctr, Breast Canc Program, Washington, DC USA

来源：

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA | 2001年 / 6卷 / 04期

关键词：

breast cancer; prognostic factors; adjuvant systemic therapy; tumor marker utility grading system;

D O I：

10.1023/A:1014778713034

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Decisions regarding the use of adjuvant therapy for breast cancer are strongly influenced by the risk of disease recurrence and death. These risks are now determined by, examining the currently recognized breast cancer prognostic factors, including clinical stage, axillary nodal status. tumor size and grade, hormone receptor status. and presence of lymphovascular involvement. Newer factors are being evaluated in an attempt to more precisely define disease-related prognosis. This paper provides an overview of issues that need to be considered when analyzing studies of prognostic factors as well as a review of the currently recognized and the newer candidate prognostic factors.

引用

页码：375 / 392

页数：18

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