Preparation of conjugated linoleic acid from safflower oil

被引:46
作者
Ma, DWL
Wierzbicki, AA
Field, CJ
Clandinin, MT [1 ]
机构
[1] Univ Alberta, Agr Forestry Ctr 410, Nutr & Metab Res Grp, Edmonton, AB T6G 2P5, Canada
[2] Univ Alberta, Dept Med, Edmonton, AB T6G 2P5, Canada
[3] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB T6G 2P5, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
conjugated linoleic acid; safflower oil; urea crystallization;
D O I
10.1007/s11746-999-0167-3
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Synthetically prepared mixtures of conjugated linoleic acid (CLA) are widely used in animal and cell culture studies to investigate the potential effects of the Delta 9c, 11t-18:2 isomer found in food products from ruminant animals. Alkali isomerization of linoleic acid is a common method used in the synthesis of a mixture of CLA isomers containing predominantly the Delta 9c,11t-18:2 and Delta 10t,12c-18:2 isomers. Some biological activity might also be mediated by the Delta 10t,12c-18:2 isomer. Currently few published methodologies exist describing procedures for the enrichment of these two isomers. A method is described herein to take advantage of an inexpensive oil, safflower oil, for use in synthesis of CLA and a procedure to enrich the Delta 10t, 12c-18:2 isomer.
引用
收藏
页码:729 / 730
页数:2
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