Fused tetracycles with a benzene or cyclohexadiene core: [2+2+2] cycloadditions on macrocyclic systems

被引：29

作者：

Brun, Sandra ^{[1
]}

Garcia, Lidia ^{[1
]}

Gonzalez, Ivan ^{[1
]}

Torrent, Anna ^{[1
]}

Dachs, Anna ^{[1
]}

Pla-Quintana, Anna ^{[1
]}

Parella, Teodor ^{[2
]}

Roglans, Anna ^{[1
]}

机构：

[1] Univ Girona, Dept Chem, E-17071 Girona, Spain

[2] Univ Autonoma Barcelona, Servei RMN, E-08193 Barcelona, Spain

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 36期

关键词：

D O I：

10.1039/b806524a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of fused tetracycles with a benzene or cyclohexadiene core (2a-h) is satisfactorily prepared by intramolecular [2 + 2 + 2] cycloadditions of triynic and enediynic macrocycles (1a-h) under RhCl(PPh3)(3) catalysis; the enantioselective cycloaddition of macrocycles 1b and le gives chiral tetracycles with moderate enantiomeric excess.

引用

页码：4339 / 4341

页数：3

共 34 条

[31] Enantioselective synthesis of planar-chiral metacyclophanes through rhodium-catalyzed alkyne cyclotrimerization [J].