Sensitive and selective viral DNA detection assay via microbead-based rolling circle amplification

被引:22
作者
Schopf, Eric [1 ,2 ]
Fischer, Nicholas O. [1 ]
Chen, Yong [2 ]
Tok, Jeffrey B. -H. [1 ]
机构
[1] Lawrence Livermore Natl Lab, BioSecur & NanoSci Lab, Livermore, CA 94551 USA
[2] Univ Calif Los Angeles, Dept Mech & Aerosp Engn, Los Angeles, CA 90095 USA
关键词
Rolling circle amplification; Magnetic beads; Viral DNA; Real-time detection;
D O I
10.1016/j.bmcl.2008.07.064
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
We report a sensitive and efficient magnetic bead-based assay for viral DNA identification using isothermal amplification of a reporting probe. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5871 / 5874
页数:4
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