Multiplexed DNA detection with biobarcoded nanoparticle probes

被引：223

作者：

Stoeva, Savka I.

Lee, Jae-Seung

Thaxton, C. Shad

Mirkin, Chad A.

机构：

[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[2] Northwestern Univ, Int Inst Nanotechnol, Evanston, IL 60208 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 20期

关键词：

barcodes; biosensors; DNA detection; gold; nanoparticles;

D O I：

10.1002/anie.200600124

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：3303 / 3306

页数：4

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