Microfluidics and photonics for Bio-System-on-a-Chip: A review of advancements in technology towards a microfluidic flow cytometry chip

被引：130

作者：

Godin, Jessica ^{[1
]}

Chen, Chun-Hao ^{[1
]}

Cho, Sung Hwan ^{[1
]}

Qiao, Wen ^{[2
]}

Tsai, Frank ^{[1
]}

Lo, Yu-Hwa ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA

[2] Zhejiang Univ, State Key Lab, Natl Engn Res Ctr Opt Instrument, Hangzhou, Zhejiang, Peoples R China

来源：

JOURNAL OF BIOPHOTONICS | 2008年 / 1卷 / 05期

关键词：

Biomedical instrumentation and transducers; including micro-electro-mechanical systems (MEMS); cells on a chip; other integrated-optical elements and systems; fabrication techniques; lithography; pattern transfer; flows in micro-electromechanical systems (MEMS) and nanoelectromechanical systems (NEMS); fluorescence;

D O I：

10.1002/jbio.200810018

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to familiarize a reader with the current state of the technologies and also highlights the requirements of the device and how researchers are working to meet these needs A microfluidic flow cytometer prototype employing on-chip lenses for illumination and light collection in conjunction with a microfluidic sample flow system for device miniaturization.

引用

页码：355 / 376

页数：22

共 111 条

[31]

FU AYC, MICROFABRICATED FLUO, P115

[32] Electrokinetically driven micro flow cytometers with integrated fiber optics for on-line cell/particle detection [J].

Fu, LM ;

Yang, RJ ;

Lin, CH ;

Pan, YJ ;

Lee, GB .

ANALYTICA CHIMICA ACTA, 2004, 507 (01) :163-169

[33] Electrokinetic focusing injection methods on microfluidic devices [J].

Fu, LM ;

Yang, RJ ;

Lee, GB .

ANALYTICAL CHEMISTRY, 2003, 75 (08) :1905-1910

[34] Microfluidic tunable dye laser with integrated mixer and ring resonator [J].

Galas, JC ;

Torres, J ;

Belotti, M ;

Kou, Q ;

Chen, Y .

APPLIED PHYSICS LETTERS, 2005, 86 (26) :1-3

[35]

Givan, 2001, FLOW CYTOMETRY 1 PRI, DOI 10.1002/0471223948

[36] Toolkit for computational fluidic simulation and interactive parametrization of segmented flow based fluidic networks [J].

Gleichmann, Nils ;

Malsch, Daniell ;

Kielpinski, Mark ;

Rossak, Wilhelm ;

Mayer, Guenter ;

Henkel, Thomas .

CHEMICAL ENGINEERING JOURNAL, 2008, 135 (SUPPL. 1) :S210-S218

[37] Single particle high resolution spectral analysis flow cytometry [J].

Goddard, Gregory ;

Martin, John C. ;

Naivar, Mark ;

Goodwin, Peter M. ;

Graves, Steven W. ;

Habbersett, Robb ;

Nolan, John P. ;

Jett, James H. .

CYTOMETRY PART A, 2006, 69A (08) :842-851

[38]

GODIN J, 2006, LASERS ELECTROOPTICS, V605

[39] Demonstration of two-dimensional fluidic lens for integration into microfluidic flow cytometers [J].

Godin, Jessica ;

Lien, Victor ;

Lo, Yu-Hwa .

APPLIED PHYSICS LETTERS, 2006, 89 (06)

[40] Microfluidic memory and control devices [J].

Groisman, A ;

Enzelberger, M ;

Quake, SR .

SCIENCE, 2003, 300 (5621) :955-958

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