Genetic support and diversity of acquired extended-spectrum β-lactamases in Gram-negative rods

被引：123

作者：

Poirel, Laurent

Bonnin, Remy A.

Nordmann, Patrice

机构：

[1] Hop Bicetre, AP HP, Serv Bacteriol Virol, INSERM Emerging Resistance Antibiot U914,Fac Med, K Bicetre, France

[2] Univ Paris 11, K Bicetre, France

来源：

INFECTION GENETICS AND EVOLUTION | 2012年 / 12卷 / 05期

关键词：

beta-Lactamases; Integron; Transposon; Insertion sequence; ESBL; CLASS; 3; INTEGRON; ACINETOBACTER-BAUMANNII; PSEUDOMONAS-AERUGINOSA; ESCHERICHIA-COLI; ANTIBIOTIC-RESISTANCE; CTX-M; KLEBSIELLA-PNEUMONIAE; CLASS-1; MULTIDRUG-RESISTANCE; CLINICAL ISOLATE;

D O I：

10.1016/j.meegid.2012.02.008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Genes encoding extended-spectrum beta-lactamases (ESBLs) have been reported in a variety of Gram-negative species, mostly in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii. They are either TEM- or SHV-derivatives, CTX-M-like enzymes and less frequently of the GES, PER, or VEB types. The mechanisms at the origin of their acquisition are diverse, and mostly are related to insertion sequences, transposons and class 1 integrons. This diversity of genetic vehicles at the origin of these mobilization/acquisition processes may explain spread of ESBLs worldwide. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：883 / 893

页数：11

共 112 条

[1] Genetic Basis of Multidrug Resistance in Acinetobacter baumannii Clinical Isolates at a Tertiary Medical Center in Pennsylvania [J].

Adams-Haduch, Jennifer M. ;

Paterson, David L. ;

Sidjabat, Hanna E. ;

Pasculle, Anthony W. ;

Potoski, Brian A. ;

Muto, Carlene A. ;

Harrison, Lee H. ;

Doi, Yohei .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (11) :3837-3843

[2] Widespread transfer of resistance genes between bacterial species in an intensive care unit: Implications for hospital epidemiology [J].

Al Naiemi, N ;

Duim, B ;

Savelkoul, PHM ;

Spanjaard, L ;

de Jonge, E ;

Bart, A ;

Vandenbroucke-Grauls, CA ;

de Jong, MD .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (09) :4862-4864

[3] Nosocomial bacteremia and urinary tract infections caused by extended-spectrum β-lactamase producing Klebsiella pneumoniae with plasmids carrying both SHV-5 and TLA-1 genes [J].

Alcantar-Curiel, D ;

Tinoco, JC ;

Gayosso, C ;

Carlos, A ;

Daza, C ;

Perez-Prado, MC ;

Salcido, L ;

Santos, JI ;

Alpuche-Aranda, CM .

CLINICAL INFECTIOUS DISEASES, 2004, 38 (08) :1067-1074

[4] A STANDARD NUMBERING SCHEME FOR THE CLASS-A BETA-LACTAMASES [J].

AMBLER, RP ;

COULSON, AFW ;

FRERE, JM ;

GHUYSEN, JM ;

JORIS, B ;

FORSMAN, M ;

LEVESQUE, RC ;

TIRABY, G ;

WALEY, SG .

BIOCHEMICAL JOURNAL, 1991, 276 :269-270

[5] Novel genetic structure associated with an extended-spectrum β-lactamase blaVEBGene in a Providencia stuartii clinical isolate from Algeria [J].

Aubert, D ;

Naas, T ;

Lartigue, MF ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (08) :3590-3592

[6] Functional and structural characterization of the genetic environment of an extended-spectrum β-lactamase blaVEB gene from a Pseudomonas aeruginosa isolate obtained in India [J].

Aubert, D ;

Girlich, D ;

Naas, T ;

Nagarajan, S ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (09) :3284-3290

[7] ANALYSIS OF THE VARIABLE ENDPOINTS GENERATED BY ONE-ENDED TRANSPOSITION OF TN21 [J].

AVILA, P ;

GRINSTED, J ;

DELACRUZ, F .

JOURNAL OF BACTERIOLOGY, 1988, 170 (03) :1350-1353

[8] Distribution of the blaTEM gene and blaTEM-containing transposons in commensal Escherichia coli [J].

Bailey, Jannine K. ;

Pinyon, Jeremy L. ;

Anantham, Sashindran ;

Hall, Ruth M. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (04) :745-751

[9] Characterization of beta-lactamase gene bla(PER-2,) which encodes an extended-spectrum class A beta-lactamase [J].

Bauernfeind, A ;

Stemplinger, I ;

Jungwirth, R ;

Mangold, P ;

Amann, S ;

Akalin, E ;

Ang, O ;

Bal, C ;

Casellas, JM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (03) :616-620

[10] A NEW PLASMIDIC CEFOTAXIMASE IN A CLINICAL ISOLATE OF ESCHERICHIA-COLI [J].

BAUERNFEIND, A ;

GRIMM, H ;

SCHWEIGHART, S .

INFECTION, 1990, 18 (05) :294-298

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