Antifungal metabolites from the marine sponge Pachastrissa sp.:: New bengamide and bengazole derivatives

被引：51

作者：

Fernández, R

Dherbomez, M

Letourneux, Y ^{[1
]}

Nabil, M

Verbist, JF

Biard, JF

机构：

[1] Univ La Rochelle, Lab SESNAB, F-17042 La Rochelle 1, France

[2] Univ Nantes, Fac Pharm, Grp SMAB, ISOMer, F-44035 Nantes, France

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 05期

关键词：

D O I：

10.1021/np980330l

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

This paper reports the studies of components of an undescribed sponge in the genus Pachastrissa sp., collected along the Djibouti coast. The extract showed activity against Candida albicans. Six new bengazoles (1-6) and a new bengamide, named bengamide L (16), in addition to the known bengazoles (7-11), bengamides A (12), B (13), E (14), and F (15), and a lactone (17) are described in this paper. All structures were determined on the basis of spectroscopic studies.

引用

页码：678 / 680

页数：3

共 6 条

[1] NOVEL SPONGE-DERIVED AMINO-ACIDS .5. STRUCTURES, STEREOCHEMISTRY, AND SYNTHESIS OF SEVERAL NEW HETEROCYCLES [J].