Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: A Monte Carlo study

被引:58
作者
Bues, M [1 ]
Newhauser, WD [1 ]
Titt, U [1 ]
Smith, AR [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Radiat Phys, Houston, TX 77030 USA
关键词
D O I
10.1093/rpd/nci259
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In step and shoot spot-scanning, a small-diameter proton beam is magnetically swept and varied in energy in order to cover the tumour. Initial estimates of the beam size indicate that additional collimating hardware will be needed for lower energy proton beams in order to achieve a clinically acceptable lateral dose falloff at the edge of the proton beam. In this report, we present dosimetric data from Monte Carlo simulations with a model of a simple multileaf collimator which indicate that such a device may be used to improve the lateral dose falloff. The dosimetric quantities relevant to the clinical usefulness of the device are studied, including lateral penumbra, leaf transmission and scalloping effect. Multileaf collimation is compared with a differential spot-weighting technique of sharpening the lateral dose falloff.
引用
收藏
页码:164 / 169
页数:6
相关论文
共 10 条
[1]  
[Anonymous], 1993, PENETRATION PROTON B
[2]  
BERGER MJ, 1993, 5330 NISTIR
[3]   CLINICAL DOSIMETRY FOR IMPLEMENTATION OF A MULTILEAF COLLIMATOR [J].
BOYER, AL ;
OCHRAN, TG ;
NYERICK, CE ;
WALDRON, TJ ;
HUNTZINGER, CJ .
MEDICAL PHYSICS, 1992, 19 (05) :1255-1261
[4]  
Breuer H, 2000, PROTON THERAPY RADIO
[5]   MAGNETIC SCANNING SYSTEM FOR HEAVY-ION THERAPY [J].
HABERER, T ;
BECHER, W ;
SCHARDT, D ;
KRAFT, G .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1993, 330 (1-2) :296-305
[6]  
HENDRICKS JS, 2004, MCNPX VERSION 2 5 C
[7]   Intensity modulation methods for proton radiotherapy [J].
Lomax, A .
PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (01) :185-205
[8]   A model for the lateral penumbra in water of a 200-MeV proton beam devoted to clinical applications [J].
Oozeer, R ;
Mazal, A ;
Rosenwald, JC ;
Belshi, R ;
Nauraye, C ;
Ferrand, R ;
Biensan, S .
MEDICAL PHYSICS, 1997, 24 (10) :1599-1604
[9]   THE 200-MEV PROTON THERAPY PROJECT AT THE PAUL-SCHERRER-INSTITUTE - CONCEPTUAL DESIGN AND PRACTICAL REALIZATION [J].
PEDRONI, E ;
BACHER, R ;
BLATTMANN, H ;
BOHRINGER, T ;
CORAY, A ;
LOMAX, A ;
LIN, SX ;
MUNKEL, G ;
SCHEIB, S ;
SCHNEIDER, U ;
TOUROVSKY, A .
MEDICAL PHYSICS, 1995, 22 (01) :37-53
[10]   RADIOLOGICAL USE OF FAST PROTONS [J].
WILSON, RR .
RADIOLOGY, 1946, 47 (05) :487-491