17β-Hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family;: nomenclature and main characteristics of the 17HSD/KSR enzymes

被引：259

作者：

Peltoketo, H ^{[1
]}

Luu-The, V

Simard, J

Adamski, J

机构：

[1] Univ Oulu, Bioctr Oulu, FIN-90220 Oulu, Finland

[2] Univ Oulu, WHO Collaborating Ctr Res Reprod Hlth, FIN-90220 Oulu, Finland

[3] CHUL Res Ctr, MRC, Grp Mol Endocrinol, Quebec City, PQ, Canada

[4] Univ Laval, Quebec City, PQ, Canada

[5] GSF, Natl Res Ctr hlth & Environm, Inst Mammalian Genet, Genome Anal Ctr, Neuherberg, Germany

来源：

JOURNAL OF MOLECULAR ENDOCRINOLOGY | 1999年 / 23卷 / 01期

关键词：

D O I：

10.1677/jme.0.0230001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A number of enzymes possessing 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activities have been described and cloned, but their nomenclature needs specification. To clarify the present situation, descriptions of the eight cloned 17HSD/KSRs are given and guidelines for the classification of novel 17HSD/KSR enzymes are presented.

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页码：1 / 11

页数：11

相关论文

共 86 条

[51] DISTRIBUTION OF 17-BETA-HYDROXYSTEROID DEHYDROGENASE GENE-EXPRESSION AND ACTIVITY IN RAT AND HUMAN TISSUES [J].

MARTEL, C ;

RHEAUME, E ;

TAKAHASHI, M ;

TRUDEL, C ;

COUET, J ;

LUUTHE, V ;

SIMARD, J ;

LABRIE, F .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1992, 41 (3-8) :597-603

[52] KE-6-GENE - SEQUENCE AND ORGANIZATION AND ABERRANT REGULATION IN MURINE POLYCYSTIC KIDNEY-DISEASE [J].

MAXWELL, MM ;

NEARING, J ;

AZIZ, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (42) :25213-25219

[53] Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression [J].

Miettinen, MM ;

Mustonen, MVJ ;

Poutanen, MH ;

Isomaa, VV ;

Vihko, RK .

BIOCHEMICAL JOURNAL, 1996, 314 :839-845

[54] 17-BETA-HYDROXYSTEROID OXIDOREDUCTASE - A UBIQUITOUS ENZYME - INTERCONVERSION OF ESTRONE AND ESTRADIOL-17-BETA IN BALB/C MOUSE-TISSUES [J].

MILEWICH, L ;

GARCIA, RL ;

GERRITY, LW .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1985, 34 (10) :938-944

[55] Cell type-specific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver [J].

Moghrabi, N ;

Head, JR ;

Andersson, S .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (11) :3872-3878

[56]

MOLLER G, 1999, IN PRESS J STEROID B, V4

[57] HUMAN PLACENTAL ESTRADIOL 17-BETA-DEHYDROGENASE - SEQUENCE OF A HISTIDINE-BEARING PEPTIDE IN THE CATALYTIC REGION [J].

MURDOCK, GL ;

CHIN, CC ;

WARREN, JC .

BIOCHEMISTRY, 1986, 25 (03) :641-646

[58] Ontogeny of 17 beta-hydroxysteroid dehydrogenase type 2 mRNA expression in the developing mouse placenta and fetus [J].

Mustonen, M ;

Poutanen, M ;

ChotteauLelievre, A ;

deLaunoit, Y ;

Isomaa, V ;

Vainio, S ;

Vihko, R ;

Vihko, P .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1997, 134 (01) :33-40

[59] Mouse 17β-hydroxysteroid dehydrogenase type 2 mRNA is predominantly expressed in hepatocytes and in surface epithelial cells of the gastrointestinal and urinary tracts [J].

Mustonen, MVJ ;

Poutanen, MH ;

Kellokumpu, S ;

de Launoit, Y ;

Isomaa, VV ;

Vihko, RK ;

Vihko, PT .

JOURNAL OF MOLECULAR ENDOCRINOLOGY, 1998, 20 (01) :67-74

[60] Cloning of mouse 17 beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues [J].

Mustonen, MVJ ;

Poutanen, MH ;

Isomaa, VV ;

Vihko, PT ;

Vihko, RK .

BIOCHEMICAL JOURNAL, 1997, 325 :199-205

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