Effects of OspA vaccination on Lyme disease serologic testing

被引：19

作者：

Aguero-Rosenfeld, ME

Roberge, J

Carbonaro, CA

Nowakowski, J

Nadelman, RB

Wormser, GP

机构：

[1] Westchester Cty Med Ctr, Clin Labs, Valhalla, NY 10595 USA

[2] New York Med Coll, Dept Pathol, Valhalla, NY 10595 USA

[3] New York Med Coll, Dept Med, Div Infect Dis, Valhalla, NY 10595 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 11期

关键词：

D O I：

10.1128/JCM.37.11.3718-3721.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study presents the effects of OspA vaccination on two-step testing for Borrelia burgdorferi antibodies. Although vaccinees developed enzyme-linked immunosorbent assay reactivity, immunoblots did not fulfill Centers for Disease Control and Prevention criteria for positivity. Furthermore, OspA reactivity did not interfere with interpretation of immunoblots with sera from patients who developed early Lyme disease despite vaccination.

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收藏

页码：3718 / 3721

页数：4

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