Serological identification of human tumor antigens

被引：254

作者：

Sahin, U

Tureci, O

Pfreundschuh, M

机构：

[1] Madizinische Klinik I, Univ. des Saarlandes, D-66421, Homburg

来源：

CURRENT OPINION IN IMMUNOLOGY | 1997年 / 9卷 / 05期

关键词：

D O I：

10.1016/S0952-7915(97)80053-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Using the antibody repertoire of cancer patients for the systematic search for human tumor antigens, a plenitude of new human tumor antigens has been identified demonstrating that many human tumors elicit multiple immune responses in the autologous host. The abundance of serologically defined human tumor antigens facilitates the identification of T cell dependent antigens and provides a basis for peptide and gene therapy vaccine strategies in a wide variety of human cancers.

引用

页码：709 / 716

页数：8

共 83 条

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