Presence of the KPC Carbapenemase Gene in Enterobacteriaceae Causing Bacteremia and Its Correlation with In Vitro Carbapenem Susceptibility

被引:28
作者
Marschall, Jonas [1 ]
Tibbetts, Robert J. [2 ]
Dunne, W. Michael, Jr. [2 ]
Frye, Jonathan G. [3 ]
Fraser, Victoria J. [1 ]
Warren, David K. [1 ]
机构
[1] Washington Univ, Sch Med, Div Infect Dis, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Div Lab Med, St Louis, MO 63110 USA
[3] ARS, Bacterial Epidemiol & Antimicrobial Resistance Re, USDA, Athens, GA USA
基金
瑞士国家科学基金会;
关键词
HYDROLYZING BETA-LACTAMASE; BLOOD-STREAM INFECTIONS; GRAM-NEGATIVE BACTERIA; KLEBSIELLA-PNEUMONIAE; NEW-YORK; PSEUDOMONAS-AERUGINOSA; BROOKLYN; RESISTANCE; SPREAD; EPIDEMIOLOGY;
D O I
10.1128/JCM.02123-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of (KPC)-K-bla, a transferable carbapenemase gene. Three (1.2%) out of 243 isolates were (KPC)-K-bla positive. Ertapenem nonsusceptibility had a low positive predictive value.
引用
收藏
页码:239 / 241
页数:3
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