Detection and spread of Escherichia coli possessing the plasmid-borne carbapenemase KPC-2 in Brooklyn, New York

被引:94
作者
Bratu, Simona
Brooks, Steven
Burney, Sibte
Kochar, Sandeep
Gupta, Jyoti
Landman, David
Quale, John
机构
[1] Suny Downstate Med Ctr, Brooklyn, NY 11203 USA
[2] Kingsbrook Jewish Med Ctr, Brooklyn, NY USA
[3] Brookdale Univ Med Ctr, Brooklyn, NY USA
关键词
D O I
10.1086/512370
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A carbapenem- resistant isolate of Escherichia coli was identified that possessed a 23- kb plasmid encoding Klebsiella pneumoniae carbapenemase type 2 (KPC- 2). A subsequent surveillance study involving hospitals in Brooklyn, New York, revealed that, among 1417 E. coli isolates, 7 isolates (from 3 hospitals) possessed bla(KPC-2). E. coli possessing KPC-2 is emerging in our region, and improved methods for detection are urgently needed.
引用
收藏
页码:972 / 975
页数:4
相关论文
共 29 条
[1]  
[Anonymous], [No title captured]
[2]   Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 β-lactamases in New York City [J].
Bradford, PA ;
Bratu, S ;
Urban, C ;
Visalli, M ;
Mariano, N ;
Landman, D ;
Rahal, JJ ;
Brooks, S ;
Cebular, S ;
Quale, J .
CLINICAL INFECTIOUS DISEASES, 2004, 39 (01) :55-60
[3]   Detection of KPC carbapenem-hydrolyzing enzymes in Enterobacter spp. from Brooklyn, New York [J].
Bratu, S ;
Landman, D ;
Alam, M ;
Tolentino, E ;
Quale, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (02) :776-778
[4]   Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City -: A new threat to our antibiotic armamentarium [J].
Bratu, S ;
Landman, D ;
Haag, R ;
Recco, R ;
Eramo, A ;
Alam, M ;
Quale, J .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (12) :1430-1435
[5]   Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York:: Epidemiology and recommendations for detection [J].
Bratu, S ;
Mooty, M ;
Nichani, S ;
Landman, D ;
Gullans, C ;
Pettinato, B ;
Karumudi, U ;
Tolaney, P ;
Quale, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) :3018-3020
[6]   DIFFUSION OF MEROPENEM AND IMIPENEM THROUGH THE OUTER-MEMBRANE OF ESCHERICHIA-COLI-K-12 AND CORRELATION WITH THEIR ANTIBACTERIAL ACTIVITIES [J].
CORNAGLIA, G ;
GUAN, LM ;
FONTANA, R ;
SATTA, G .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (09) :1902-1908
[7]   Escherichia coli:: Development of carbapenem resistance during therapy [J].
Hong, T ;
Moland, ES ;
Abdalhamid, B ;
Hanson, ND ;
Wang, J ;
Sloan, C ;
Fabian, D ;
Faraiallah, A ;
Levine, J ;
Thomson, KS .
CLINICAL INFECTIOUS DISEASES, 2005, 40 (10) :E84-E86
[8]   Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp. [J].
Hossain, A ;
Ferraro, MJ ;
Pino, RM ;
Dew, RB ;
Moland, ES ;
Lockhart, TJ ;
Thomson, KS ;
Goering, RV ;
Hanson, ND .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (11) :4438-4440
[9]   Screening for antibiotic resistant Gram-negative bacteria [J].
Iredell, Jonathan R. ;
Sintchenko, Vitali .
LANCET INFECTIOUS DISEASES, 2006, 6 (06) :316-317
[10]   Imipenem resistance in a Salmonella clinical strain due to plasmid-mediated class a carbapenemase KPC-2 [J].
Miriagou, V ;
Tzouvelekis, LS ;
Rossiter, S ;
Tzelepi, E ;
Angulo, FJ ;
Whichard, JA .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (04) :1297-1300