Escherichia coli:: Development of carbapenem resistance during therapy

被引：55

作者：

Hong, T

Moland, ES

Abdalhamid, B

Hanson, ND

Wang, J

Sloan, C

Fabian, D

Faraiallah, A

Levine, J

Thomson, KS

机构：

[1] Hackensack Univ, Med Ctr, Clin Microbiol Lab, Hackensack, NJ 07601 USA

[2] Creighton Univ, Omaha, NE 68178 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 10期

关键词：

D O I：

10.1086/429822

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 76-year-old woman had recurrent urosepsis due to extended-spectrum beta-lactamase-positive Escherichia coli. Imipenem resistance was detected after long-term imipenem-meropenem therapy. The carbapenem-hydrolyzing enzyme gene was identified as bla(KPC-3). To our knowledge, this is the first documented case in which carbapenem-resistant E coli emerged during therapy with imipenem and meropenem, and the first identification of the carbapenem-hydrolyzing enzyme in E. coli isolates.

引用

页码：E84 / E86

页数：3

共 6 条

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