Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

被引：92

作者：

Hossain, A

Ferraro, MJ

Pino, RM

Dew, RB

Moland, ES

Lockhart, TJ

Thomson, KS

Goering, RV

Hanson, ND

机构：

[1] Creighton Univ, Sch Med, Dept Med Microbiol & Immunol, Omaha, NE 68178 USA

[2] Creighton Univ, Sch Med, Ctr Res Anti Infect & Biotechnol, Omaha, NE 68178 USA

[3] Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 11期

关键词：

D O I：

10.1128/AAC.48.11.4438-4440.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 beta-lactamase by an Enterobacter sp.

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页码：4438 / 4440

页数：3

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