Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 β-lactamases in New York City

被引：369

作者：

Bradford, PA

Bratu, S

Urban, C

Visalli, M

Mariano, N

Landman, D

Rahal, JJ

Brooks, S

Cebular, S

Quale, J

机构：

[1] SUNY Downstate, Div Infect Dis, Brooklyn, NY 11203 USA

[2] Wyeth Res, Pearl River, NY USA

[3] Kingsbrook Jewish Med Ctr, Brooklyn, NY USA

[4] New York Hosp Queens, Flushing, NY USA

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 01期

关键词：

D O I：

10.1086/421495

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nineteen isolates of carbapenem-resistant Klebsiella species were recovered from 7 hospitals in New York City. Most K. pneumoniae belonged to a single ribotype. Nucleotide sequencing identified KPC-2, a carbapenemhydrolyzing beta-lactamase. In 3 strains, TEM-30, an inhibitor-resistant beta-lactamase, was detected. Carbapenem-resistant Klebsiella species possessing KPC-2 are endemic in New York City. This study documents the identification of an inhibitor-resistant TEM beta-lactamase in the United States.

引用

页码：55 / 60

页数：6

共 33 条

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