One from column A and two from column B: the benefits of phage display in molecular-recognition studies

被引：40

作者：

Rodi, DJ ^{[1
]}

Makowski, L ^{[1
]}

Kay, BK ^{[1
]}

机构：

[1] Argonne Natl Lab, Biosci Div, Combinatorial Biol Unit, Argonne, IL 60439 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 01期

关键词：

D O I：

10.1016/S1367-5931(01)00287-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent uses of phage-displayed combinatorial peptide and cDNA libraries have proven invaluable in mapping protein-protein interactions, protein-drug interactions, and the generation of 'molecular therapeutics'. This article reviews some of the findings of the past year and points out some of the pros and cons of phage display as compared with those of yeast two-hybrid screening.

引用

页码：92 / 96

页数：5

共 42 条

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