Defining and quantifying the social phenotype in autism

被引:279
作者
Klin, A [1 ]
Jones, W [1 ]
Schultz, R [1 ]
Volkmar, F [1 ]
Cohen, D [1 ]
机构
[1] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT 06520 USA
关键词
D O I
10.1176/appi.ajp.159.6.895
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective. Genetic and neurofunctional research in autism has highlighted the need for improved characterization of the core social disorder defining the broad spectrum of syndrome manifestations. Method: This article reviews the advantages and limitations of current methods for the refinement and quantification of this highly heterogeneous social phenotype. Results. The study of social visual pursuit by use of eye-tracking technology is offered as a paradigm for novel tools incorporating these requirements and as a research effort that builds on the emerging synergy of different branches of social neuroscience. Conclusions: Advances in the area will require increased consideration of processes underlying experimental results and a closer approximation of experimental methods to the naturalistic demands inherent in real-life social situations.
引用
收藏
页码:895 / 908
页数:14
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