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Apicomplexan plastids as drug targets

被引：188
作者：
McFadden, GI [1 ]
Roos, DS
机构：
[1] Univ Melbourne, Sch Bot, Plant Cell Biol Res Ctr, Parkville, Vic 3052, Australia
[2] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA
来源：
TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 08期
基金：
澳大利亚研究理事会; 美国国家卫生研究院;
关键词：
D O I：
10.1016/S0966-842X(99)01547-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Prokaryotic metabolic pathways in the relict plastid of apicomplexan parasites make this organelle a promising target for drug development. The parasiticidal activity of several herbicides and antibacterial antibiotics is suspected to be a result of their ability to inhibit key plastid activities.
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收藏
页码：328 / 333
页数：6
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