Preparation, indications and results of human amniotic membrane transplantation for ocular surface disorders

被引：21

作者：

Alió, JL ^{[1
]}

Abad, M ^{[1
]}

Scorsetti, DH ^{[1
]}

机构：

[1] Miguel Hernandez Univ, Inst Oftalmol Alicante, Res Dev & Innovat Dept, Alicante, Spain

来源：

EXPERT REVIEW OF MEDICAL DEVICES | 2005年 / 2卷 / 02期

关键词：

amniotic membrane; ocular indications; ocular surface reconstruction; persistent epithelial defect; stem cell deficiency;

D O I：

10.1586/17434440.2.2.153

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In comparison with other biologic tissues used as reconstructive grafts, the amniotic membrane has the advantage that it is thinner and better tolerated by the patient. Amniotic membrane, when appropriately preserved, can be used as a substrate replacement, such that host cells can migrate into the membrane to form new and healthy tissue. The amniotic membrane is the deeper layer of the fetal membrane; it is avascular, multilayered tissue with antiangiogenic, antiscarring and anti-inflammatory properties. SinceiIt does not express antigens of histocompatibility, the membrane Is never rejected by the receiving tissues. In addition, the beneficial effects of reducing Inflammation and neovascularization persist for a long time, if properly cryopreserved.

引用

页码：153 / 160

页数：8

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