Organelle positioning and cell polarity

被引：135

作者：

Bornens, Michel ^{[1
]}

机构：

[1] Inst Curie, CNRS, UMR 144, F-75248 Paris 05, France

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2008年 / 9卷 / 11期

关键词：

D O I：

10.1038/nrm2524

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In spite of conspicuous differences in their polarized architecture, swimming unicellular eukaryotes and migrating cells from metazoa display a conserved hierarchical interlocking of the main cellular compartments, in which the microtubule network has a dominant role. A microtubule array can organize the distribution of endomembranes owing to a cell-wide and polarized extension around a unique nucleus-associated structure. The nucleus-associated structure in animal cells contains a highly conserved organelle, the centriole or basal body. This organelle has a defined polarity that can be transmitted to the cell. Its conservative mode of duplication seems to be a core mechanism for the transmission of polarities through cell division.

引用

页码：874 / 886

页数：13

共 172 条

[1] Microtubule release from the centrosome in migrating cells [J].

Abal, M ;

Piel, M ;

Bouckson-Castaing, V ;

Mogensen, M ;

Sibarita, JB ;

Bornens, M .

JOURNAL OF CELL BIOLOGY, 2002, 159 (05) :731-737

[2] Basal Body Positioning Is Controlled by Flagellum Formation in Trypanosoma brucei [J].

Absalon, Sabrina ;

Kohl, Linda ;

Branche, Carole ;

Blisnick, Thierry ;

Toutirais, Geraldine ;

Rusconi, Filippo ;

Cosson, Jacky ;

Bonhivers, Melanie ;

Robinson, Derrick ;

Bastin, Philippe .

PLOS ONE, 2007, 2 (05)

[3]

Azimzadeh J., 2004, CENTROSOMES DEV DIS, P93

[4] β-Catenin is a Nek2 substrate involved in centrosome separation [J].

Bahmanyar, Shirin ;

Kaplan, Daniel D. ;

DeLuca, Jennifer G. ;

Giddings, Thomas H., Jr. ;

O'Toole, Eileen T. ;

Winey, Mark ;

Salmon, Edward D. ;

Casey, Patrick J. ;

Nelson, W. James ;

Barth, Angela I. M. .

GENES & DEVELOPMENT, 2008, 22 (01) :91-105

[5] Men and sin: What's the difference? [J].

Bardin, AJ ;

Amon, A .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (11) :815-826

[6] PARTIAL PHYLOGENY OF THE UNICELLULAR EUKARYOTES BASED ON RAPID SEQUENCING OF A PORTION OF 28S RIBOSOMAL-RNA [J].

BAROIN, A ;

PERASSO, R ;

QU, LH ;

BRUGEROLLE, G ;

BACHELLERIE, JP ;

ADOUTTE, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (10) :3474-3478

[7] Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast [J].

Barral, Y ;

Mermall, V ;

Mooseker, MS ;

Snyder, M .

MOLECULAR CELL, 2000, 5 (05) :841-851

[8] Gradients in the self-organization of the mitotic spindle [J].

Bastiaens, P ;

Caudron, M ;

Niethammer, P ;

Karsenti, E .

TRENDS IN CELL BIOLOGY, 2006, 16 (03) :125-134

[9] Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles [J].

Baumgart, Tobias ;

Hammond, Adam T. ;

Sengupta, Prabuddha ;

Hess, Samuel T. ;

Holowka, David A. ;

Baird, Barbara A. ;

Webb, Watt W. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (09) :3165-3170

[10] Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina [J].

Beaudouin, J ;

Gerlich, D ;

Daigle, N ;

Eils, R ;

Ellenberg, J .

CELL, 2002, 108 (01) :83-96

← 1 2 3 4 5 6 7 8 9 10 →