Covalent double level dynamic combinatorial libraries: selectively addressable exchange processes

被引:47
作者
Orrillo, A. Gaston [1 ]
Escalante, Andrea M. [1 ]
Furlan, Ricardo L. E. [1 ]
机构
[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, RA-2000 Rosario, Santa Fe, Argentina
关键词
D O I
10.1039/b808565j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Hydrazones and disulfides have been combined in one dynamic system: hydrazones were exchanged by acid catalysis in the presence of disulfide and a thiol group without interference; neutralization of the reaction medium turns off the exchange of hydrazones and, at the same time, activates thiolate-disulfide exchange.
引用
收藏
页码:5298 / 5300
页数:3
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