Design of biodegradable nanoparticles: a novel approach to encapsulating poorly soluble phytochemical ellagic acid

被引：62

作者：

Bala, I

Bhardwaj, V

Hariharan, S

Sitterberg, J

Bakowsky, U

Kumar, MNVR ^{[1
]}

机构：

[1] Natl Inst Pharmaceut Educ & Res, Dept Pharmaceut, SAS Nagar 160062, Punjab, India

[2] Univ Marburg, Inst Pharmaceut Technol & Biopharm, D-35037 Marburg, Germany

来源：

NANOTECHNOLOGY | 2005年 / 16卷 / 12期

关键词：

D O I：

10.1088/0957-4484/16/12/014

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 [材料科学与工程]; 080502 [材料学];

摘要：

Nanosizing of poorly water soluble drugs or incorporating them into nanoparticles to increase their Solubility and thereby the bioavailability has become a favoured approach today. This work describes a novel method for encapsulating poorly water soluble phytochemical ellagic acid that is also sparingly soluble/insoluble in routine solvents used to prepare nanoparticles.

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页码：2819 / 2822

页数：4

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