Hypervalent iodine in the synthesis of bridgehead heterocycles: A facile route to the synthesis of 6-arylimidazo[2,1-b]thiazoles using [hydroxy(tosyloxy)iodo]benzene

被引：22

作者：

Aggarwal, R ^{[1
]}

Sumran, G ^{[1
]}

机构：

[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 07期

关键词：

6-arylimidazo[2,1-b]thiazoles; hydroxy(tosyloxy)iodo]benzene; hypervalent iodine; alpha-tosyloxyketones;

D O I：

10.1080/00397910500464863

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Tosyloxyketones ( 2), readily accessible through hypervalent iodine oxidation of enolizable ketones ( 1) using [ hydroxy( tosyloxy) iodo] benzene ( HTIB) in acetonitrile, exclusively generates the 6-arylimidazo[ 2,1-b] thiazoles ( 4) on treatment with commercially available 2-aminothiazole ( 3).

引用

页码：875 / 879

页数：5

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