Microwave-enhanced synthesis of new (-)-steganacin and (-)-steganone aza analogues

被引：43

作者：

Beryozkina, T ^{[1
]}

Appukkuttan, P ^{[1
]}

Mont, N ^{[1
]}

Van der Eycken, E ^{[1
]}

机构：

[1] Univ Louvain, Dept Chem, B-3001 Louvain, Belgium

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 03期

关键词：

D O I：

10.1021/ol052766f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A novel, microwave-enhanced, highly efficient protocol for the synthesis of hitherto unknown (-)-steganacin and (-)-steganone 7-aza analogues containing a 1,2,3-triazole ring has been presented. Microwave irradiation was found to be highly beneficial in promoting the Suzuki reaction and the 1,3-dipolar cycloaddition reaction to generate the highly strained medium-sized ring system of the title molecules.

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收藏

页码：487 / 490

页数：4

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