Nodal signaling: Cryptic lefty mechanism of antagonism decoded

被引：29

作者：

Branford, WW ^{[1
]}

Yost, HJ ^{[1
]}

机构：

[1] Univ Utah, Ctr Children, Huntsman Canc Inst, Dept Oncol Sci, Salt Lake City, UT 84112 USA

来源：

CURRENT BIOLOGY | 2004年 / 14卷 / 09期

关键词：

D O I：

10.1016/j.cub.2004.04.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The secreted TGFbeta factor Lefty antagonizes Nodal signaling during vertebrate embryogenesis, but how it does so has been a mystery. Recent analyses have elucidated the molecular mechanisms underlying this function of Lefty.

引用

页码：R341 / R343

页数：3

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