Oral controlled-release dosage forms .1. Cellulose ether polymers in hydrophilic matrices

被引:91
作者
Salsa, T [1 ]
Veiga, F [1 ]
Pina, ME [1 ]
机构
[1] UNIV COIMBRA,FAC PHARM,LAB GALEN & PHARMACEUT TECHNOL,P-3049 COIMBRA,PORTUGAL
关键词
controlled-release matrices; hydrophilic matrices; cellulose ether polymers; hydroxypropylmethylcellulose; HPMC;
D O I
10.3109/03639049709148697
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An appropriately designed controlled-release drug delivery system can be a major advance towards solving problems concerning the targeting of a drug to a specific organ or tissue and controlling the rate of drug delivery to the target tissue. Hydrophilic matrices are an interesting option when developing cut oral controlled-release formulation. The present study focuses on oral controlled-release dosage forms and the application of cellulose ether polymers in hydrophilic matrices.
引用
收藏
页码:929 / 938
页数:10
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