Oral controlled-release dosage forms .1. Cellulose ether polymers in hydrophilic matrices

被引：91

作者：

Salsa, T ^{[1
]}

Veiga, F ^{[1
]}

Pina, ME ^{[1
]}

机构：

[1] UNIV COIMBRA,FAC PHARM,LAB GALEN & PHARMACEUT TECHNOL,P-3049 COIMBRA,PORTUGAL

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1997年 / 23卷 / 09期

关键词：

controlled-release matrices; hydrophilic matrices; cellulose ether polymers; hydroxypropylmethylcellulose; HPMC;

D O I：

10.3109/03639049709148697

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An appropriately designed controlled-release drug delivery system can be a major advance towards solving problems concerning the targeting of a drug to a specific organ or tissue and controlling the rate of drug delivery to the target tissue. Hydrophilic matrices are an interesting option when developing cut oral controlled-release formulation. The present study focuses on oral controlled-release dosage forms and the application of cellulose ether polymers in hydrophilic matrices.

引用

页码：929 / 938

页数：10

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