Dynamic switching between binding sites in the complexation of macrocyclic 'push-pull' chromophores to lanthanides

被引：13

作者：

Coluccini, Carmine ^{[1
]}

Pasini, Dario ^{[1
]}

Righetti, Pierpaolo ^{[1
,2
]}

Griend, Douglas A. Vander ^{[2
]}

机构：

[1] Univ Pavia, Dept Organ Chem, I-27100 Pavia, Italy

[2] Calvin Coll, Dept Chem & Biochem, Grand Rapids, MI 49546 USA

来源：

TETRAHEDRON | 2009年 / 65卷 / 50期

关键词：

Macrocycles; Lanthanides; Hill equation; 'Push-pull' chromophores; Factor analysis; Spectrophotometric titration; Sivvu; BUILDING-BLOCKS; COOPERATIVITY; LIGAND; EXTTF;

D O I：

10.1016/j.tet.2009.10.024

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

The introduction of a 1,3-diacetylpyridine moiety, as an additional binding niche in a macrocyclic receptor ligand containing a conjugated, push-pull malonate functionality, leads to, in addition to the 1:1 binding stoichiometry, the equilibrium formation of multiple complexes, specifically 1:2, 2:1, and 3:1 ligand:metal complexes with lanthanide trications. Various binding modes elicit distinctive responses in the visible region, which enhance the potential recognition of lanthanide ions. This paper also highlights the usefulness of a full factor analysis in the elucidation of complex binding phenomena. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：10436 / 10440

页数：5

共 30 条

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Lanthanide(III) chelates for NMR biomedical applications [J].