Enantiomeric excess determination of α-amino acids by 19F NMR spectroscopy of their N,N-dimethyl-(2,2,2-trifluoro-1-phenylethyl)amine-C,N)palladium complexes

被引：22

作者：

Levrat, F

Stoeckli-Evans, H

Engel, N

机构：

[1] Univ Fribourg, Dept Chem, CH-1700 Fribourg, Switzerland

[2] Univ Neuchatel, Inst Chem, CH-2007 Neuchatel, Switzerland

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 21期

关键词：

D O I：

10.1016/S0957-4166(02)00642-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis and resolution of the trifluoromethyl-palladacycle, di-mu-chloro-bis(N,N-dimethyl-(2,2,2-trifluoro-1-phenylethyl)amine-2-C,N)palladium(II) are shown. The utility of the complex and its application in the enantiomeric excess determination of alpha-amino acids by F-19 NMR spectroscopy is demonstrated and X-ray diffraction analysis of one of the diastereomeric complexes, trans-{[(R)-phenylglycinato-N,O][(R)-N,N-dimethyl-(2,2,2-trifluoro-1-phenylethyl)amine-C,N]palladium(II)}, is reported. (C) 2002 Published by Elsevier Science Ltd.

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页码：2335 / 2344

页数：10

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