Transverse NMR relaxation as a probe of mesoscopic structure

被引:40
作者
Kiselev, VG [1 ]
Novikov, DS
机构
[1] Univ Hosp Freburg, Sect Med Phys, D-79106 Freiburg, Germany
[2] MIT, Dept Phys, Cambridge, MA 02139 USA
关键词
D O I
10.1103/PhysRevLett.89.278101
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Transverse NMR relaxation in a macroscopic sample is shown to be extremely sensitive to the structure of mesoscopic magnetic susceptibility variations. Such a sensitivity is proposed as a novel kind of contrast in the NMR measurements. For suspensions of arbitrary-shaped paramagnetic objects, the transverse relaxation is found in the case of a small dephasing effect of an individual object. Strong relaxation rate dependence on the objects' shape agrees with experiments on whole blood. Demonstrated structure sensitivity is a generic effect that arises in NMR relaxation in porous media, biological systems, as well as in kinetics of diffusion limited reactions.
引用
收藏
页码:278101 / 278101
页数:4
相关论文
共 24 条
  • [1] Theory of coherent and incoherent nuclear spin dephasing in the heart
    Bauer, WR
    Nadler, W
    Bock, M
    Schad, LR
    Wacker, C
    Hartlep, A
    Ertl, G
    [J]. PHYSICAL REVIEW LETTERS, 1999, 83 (20) : 4215 - 4218
  • [2] COMPARISON OF T2 RELAXATION IN BLOOD, BRAIN, AND FERRITIN
    BROOKS, RA
    VYMAZAL, J
    BULTE, JWM
    BAUMGARNER, CD
    TRAN, V
    [J]. JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, 1995, 5 (04): : 446 - 450
  • [3] On T2-shortening by weakly magnetized particles:: The chemical exchange model
    Brooks, RA
    Moiny, F
    Gillis, P
    [J]. MAGNETIC RESONANCE IN MEDICINE, 2001, 45 (06) : 1014 - 1020
  • [4] EFFECTS OF DIFFUSION ON FREE PRECESSION IN NUCLEAR MAGNETIC RESONANCE EXPERIMENTS
    CARR, HY
    PURCELL, EM
    [J]. PHYSICAL REVIEW, 1954, 94 (03): : 630 - 638
  • [5] PROTON TRANSVERSE NUCLEAR MAGNETIC-RELAXATION IN OXIDIZED BLOOD - A NUMERICAL APPROACH
    GILLIS, P
    PETO, S
    MOINY, F
    MISPELTER, J
    CUENOD, CA
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1995, 33 (01) : 93 - 100
  • [6] NMR RELAXATION-TIMES OF BLOOD - DEPENDENCE ON FIELD-STRENGTH, OXIDATION-STATE, AND CELL INTEGRITY
    GOMORI, JM
    GROSSMAN, RI
    YUIP, C
    ASAKURA, T
    [J]. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1987, 11 (04) : 684 - 690
  • [7] SPIN ECHOES
    HAHN, EL
    [J]. PHYSICAL REVIEW, 1950, 80 (04): : 580 - 594
  • [8] Jensen JH, 2000, MAGN RESON MED, V44, P144, DOI 10.1002/1522-2594(200007)44:1<144::AID-MRM21>3.0.CO
  • [9] 2-O
  • [10] Analytical theory of susceptibility induced NMR signal dephasing in a cerebrovascular network (vol 81, pg 5696, 1998)
    Kiselev, VG
    Posse, S
    [J]. PHYSICAL REVIEW LETTERS, 1999, 83 (07) : 1487 - 1487