Iminosugars from α,β-epoxyamides.: Part 2:: Synthetic approach to hydroxylated pyrrolidine and azepane derivatives

被引：29

作者：

Assiego, C ^{[1
]}

Pino-González, MS ^{[1
]}

López-Herrera, FJ ^{[1
]}

机构：

[1] Univ Malaga, Fac Ciencias, Dept Bioquim Biol Mol & Quim Organ, E-29071 Malaga, Spain

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 12期

关键词：

homoiminosugar; azasugar; pyrrolidine; azepane; epoxyamide; epoxide opening;

D O I：

10.1016/j.tetlet.2004.01.144

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes a new synthetic route towards hydroxylated pyrrolidines and azepane derivatives starting from chiral epoxyamides. The alternate transformations on a ribose derivative alpha,beta-epoxyamide permit the construction of five or seven member rings leading to different precursors of homoiminosugars. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2611 / 2613

页数：3

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