Musical Training Shapes Structural Brain Development

被引:517
作者
Hyde, Krista L. [1 ]
Lerch, Jason [2 ]
Norton, Andrea [4 ,5 ]
Forgeard, Marie [4 ,5 ]
Winner, Ellen [3 ]
Evans, Alan C. [1 ]
Schlaug, Gottfried [4 ,5 ]
机构
[1] McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ H3A 2B4, Canada
[2] Hosp Sick Children, Mouse Imaging Ctr, Toronto, ON M5T 3H7, Canada
[3] Boston Coll, Dept Psychol, Chestnut Hill, MA 02467 USA
[4] Beth Israel Deaconess Med Ctr, Dept Neurol, Music & Neuroimaging Lab, Boston, MA 02215 USA
[5] Harvard Univ, Sch Med, Boston, MA 02215 USA
基金
美国国家科学基金会;
关键词
HUMAN CORPUS-CALLOSUM; NON-MUSICIANS; AUDITORY-CORTEX; GRAY-MATTER; CORTICAL REPRESENTATION; YOUNG-CHILDREN; MOTOR CORTEX; BROCAS AREA; ADULT-RAT; SYNAPTOGENESIS;
D O I
10.1523/JNEUROSCI.5118-08.2009
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The human brain has the remarkable capacity to alter in response to environmental demands. Training-induced structural brain changes have been demonstrated in the healthy adult human brain. However, no study has yet directly related structural brain changes to behavioral changes in the developing brain, addressing the question of whether structural brain differences seen in adults (comparing experts with matched controls) are a product of "nature" (via biological brain predispositions) or "nurture" (via early training). Longterm instrumental music training is an intense, multisensory, and motor experience and offers an ideal opportunity to study structural brain plasticity in the developing brain in correlation with behavioral changes induced by training. Here we demonstrate structural brain changes after only 15 months of musical training in early childhood, which were correlated with improvements in musically relevant motor and auditory skills. These findings shed light on brain plasticity and suggest that structural brain differences in adult experts (whether musicians or experts in other areas) are likely due to training-induced brain plasticity.
引用
收藏
页码:3019 / 3025
页数:7
相关论文
共 61 条
[1]   GLIAL HYPERTROPHY IS ASSOCIATED WITH SYNAPTOGENESIS FOLLOWING MOTOR-SKILL LEARNING, BUT NOT WITH ANGIOGENESIS FOLLOWING EXERCISE [J].
ANDERSON, BJ ;
LI, XC ;
ALCANTARA, AA ;
ISAACS, KR ;
BLACK, JE ;
GREENOUGH, WT .
GLIA, 1994, 11 (01) :73-80
[2]   Alterations in the thickness of motor cortical subregions after motor-skill learning and exercise [J].
Anderson, BJ ;
Eckburg, PB ;
Relucio, KI .
LEARNING & MEMORY, 2002, 9 (01) :1-9
[3]  
[Anonymous], 1991, WECHSLER INTELLIGENC
[4]   Specialization of the specialized in features of external human brain morphology [J].
Bangert, Marc ;
Schlaug, Gottfried .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2006, 24 (06) :1832-1834
[5]   The Mozart effect: Tracking the evolution of a scientific legend [J].
Bangerter, A ;
Heath, C .
BRITISH JOURNAL OF SOCIAL PSYCHOLOGY, 2004, 43 :605-623
[6]   Differences in gray matter between musicians and nonmusicians [J].
Bermudez, Patrick ;
Zatorre, Robert J. .
NEUROSCIENCES AND MUSIC II: FROM PERCEPTION TO PERFORMANCE, 2005, 1060 :395-399
[7]   LEARNING CAUSES SYNAPTOGENESIS, WHEREAS MOTOR-ACTIVITY CAUSES ANGIOGENESIS, IN CEREBELLAR CORTEX OF ADULT-RATS [J].
BLACK, JE ;
ISAACS, KR ;
ANDERSON, BJ ;
ALCANTARA, AA ;
GREENOUGH, WT .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (14) :5568-5572
[8]   Music training improves verbal memory [J].
Chan, AS ;
Ho, YC ;
Cheung, MC .
NATURE, 1998, 396 (6707) :128-128
[9]   AUTOMATIC 3D INTERSUBJECT REGISTRATION OF MR VOLUMETRIC DATA IN STANDARDIZED TALAIRACH SPACE [J].
COLLINS, DL ;
NEELIN, P ;
PETERS, TM ;
EVANS, AC .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1994, 18 (02) :192-205
[10]   Training-induced structural changes in the adult human brain [J].
Draganski, B. ;
May, A. .
BEHAVIOURAL BRAIN RESEARCH, 2008, 192 (01) :137-142