1H MR spectroscopy in pediatrics

被引：33

作者：

Dezortova, Monika ^{[1
]}

Hajek, Milan ^{[1
]}

机构：

[1] Inst Clin & Expt Med, Dept Diagnost & Intervent Radiol, MR Unit, Prague 14021, Czech Republic

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2008年 / 67卷 / 02期

关键词：

MR spectroscopy; pediatrics; brain; development; metabolic diseases;

D O I：

10.1016/j.ejrad.2008.02.035

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Spectral appearance and concentrations of the most prominent metabolites are affected by brain development. This knowledge is essential for the detection of pathological changes in pediatric patients. This paper discusses specific conditions of MR spectroscopic examination of children and the effects of age on MR spectra quality and quantitation of the studied metabolites. Clinical examples show several diseases that are reflected in changes in H-1 MR spectra due to pathological alterations in the biochemical pathways of the observed metabolites. Attention is given to the main metabolites such as N-acetylaspartate, creatine/phosphocreatine, cholines, lactate, inositol, etc. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：240 / 249

页数：10

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