Shockley-Ramo theorem measures conformation changes of ion channels and proteins

被引:9
作者
Eisenberg, Bob [1 ]
Nonner, Wolfgang [2 ]
机构
[1] Rush Univ, Dept Mol Biophys, Med Ctr, Chicago, IL 60612 USA
[2] Univ Miami, Miller Sch Med, Miami, FL 33136 USA
关键词
Ion channels; Shockley-Ramo; Gating current;
D O I
10.1007/s10825-006-0130-6
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Theorems are rarely used in biology because they rarely help the descriptive experimentation to which biologists are devoted. A generalization of Kirchoff's current law-theShockley-Ramo (SR) theorem [1-6]-seems an exception. SR allows interpretation of macroscopic scale 'gating' currents associated with atomic scale charge movements within proteins.
引用
收藏
页码:363 / 365
页数:3
相关论文
共 42 条
[1]   Imaging α-hemolysin with molecular dynamics:: Ionic conductance, osmotic permeability, and the electrostatic potential map [J].
Aksimentiev, A ;
Schulten, K .
BIOPHYSICAL JOURNAL, 2005, 88 (06) :3745-3761
[2]  
Almers W, 1978, Rev Physiol Biochem Pharmacol, V82, P96, DOI 10.1007/BFb0030498
[3]  
[Anonymous], MEM FELLOWS ROY SOC
[4]  
[Anonymous], J COMPUT ELECT
[5]   SODIUM-CHANNELS AND GATING CURRENTS [J].
ARMSTRONG, CM .
PHYSIOLOGICAL REVIEWS, 1981, 61 (03) :644-683
[6]  
ARMSTRONG CM, 1975, QUART REV BIOPH, V7, P179
[7]   SINGLE SODIUM-CHANNELS FROM THE SQUID GIANT-AXON [J].
BEZANILLA, F .
BIOPHYSICAL JOURNAL, 1987, 52 (06) :1087-1090
[8]   GATING OF SODIUM AND POTASSIUM CHANNELS [J].
BEZANILLA, F .
JOURNAL OF MEMBRANE BIOLOGY, 1985, 88 (02) :97-111
[9]   The voltage sensor in voltage-dependent ion channels [J].
Bezanilla, F .
PHYSIOLOGICAL REVIEWS, 2000, 80 (02) :555-592
[10]   TIME COURSE OF SODIUM INFLUX IN SQUID GIANT AXON DURING A SINGLE VOLTAGE CLAMP PULSE [J].
BEZANILLA, F ;
ROJAS, E ;
TAYLOR, RE .
JOURNAL OF PHYSIOLOGY-LONDON, 1970, 207 (01) :151-+