Shockley-Ramo theorem measures conformation changes of ion channels and proteins

被引：9

作者：

Eisenberg, Bob ^{[1
]}

Nonner, Wolfgang ^{[2
]}

机构：

[1] Rush Univ, Dept Mol Biophys, Med Ctr, Chicago, IL 60612 USA

[2] Univ Miami, Miller Sch Med, Miami, FL 33136 USA

来源：

JOURNAL OF COMPUTATIONAL ELECTRONICS | 2007年 / 6卷 / 1-3期

关键词：

Ion channels; Shockley-Ramo; Gating current;

D O I：

10.1007/s10825-006-0130-6

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Theorems are rarely used in biology because they rarely help the descriptive experimentation to which biologists are devoted. A generalization of Kirchoff's current law-theShockley-Ramo (SR) theorem [1-6]-seems an exception. SR allows interpretation of macroscopic scale 'gating' currents associated with atomic scale charge movements within proteins.

引用

页码：363 / 365

页数：3

共 42 条

[21] AN EXTENDED PROOF OF THE RAMO-SHOCKLEY THEOREM [J].

KIM, H ;

MIN, HS ;

TANG, TW ;

PARK, YJ .

SOLID-STATE ELECTRONICS, 1991, 34 (11) :1251-1253

[22]

Miller C., 1986, ION CHANNEL RECONSTI, DOI DOI 10.1007/978-1-4757-1361-9

[23] EXTRACELLULAR PATCH CLAMP - METHOD FOR RESOLVING CURRENTS THROUGH INDIVIDUAL OPEN CHANNELS IN BIOLOGICAL-MEMBRANES [J].

NEHER, E ;

SAKMANN, B ;

STEINBACH, JH .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1978, 375 (02) :219-228

[24] SINGLE-CHANNEL CURRENTS RECORDED FROM MEMBRANE OF DENERVATED FROG MUSCLE-FIBERS [J].

NEHER, E ;

SAKMANN, B .

NATURE, 1976, 260 (5554) :799-802

[25] Relating microscopic charge movement to macroscopic currents: The Ramo-Shockley theorem applied to ion channels [J].

Nonner, W ;

Peyser, A ;

Gillespie, D ;

Eisenberg, B .

BIOPHYSICAL JOURNAL, 2004, 87 (06) :3716-3722

[26]

Nonner W, 1979, Adv Cytopharmacol, V3, P345

[27] ELECTRIC CHARGE MOTION, INDUCED CURRENT, ENERGY-BALANCE, AND NOISE [J].

PELLEGRINI, B .

PHYSICAL REVIEW B, 1986, 34 (08) :5921-5924

[28]

Ramo, 1939, P IRE, V27, P584, DOI [10.1109/JRPROC.1939.228757, DOI 10.1109/JRPROC.1939.228757]

[29] Influence of the membrane potential on the free energy of an intrinsic protein [J].

Roux, B .

BIOPHYSICAL JOURNAL, 1997, 73 (06) :2980-2989

[30] Fast inactivation in Shaker K+ channels -: Properties of ionic and gating currents [J].

Roux, MJ ;

Olcese, R ;

Toro, L ;

Bezanilla, F ;

Stefani, E .

JOURNAL OF GENERAL PHYSIOLOGY, 1998, 111 (05) :625-638

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