Gi Irks GIRKs

被引：18

作者：

Kovoor, A ^{[1
]}

Lester, HA ^{[1
]}

机构：

[1] CALTECH, Div Biol 156 29, Pasadena, CA 91125 USA

来源：

NEURON | 2002年 / 33卷 / 01期

关键词：

D O I：

10.1016/S0896-6273(01)00572-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

G protein-activated potassium channels (GIRKs), monitored with the temporal and molecular resolution of electrophysiology, play a key role in the study of signal transduction. GIRKs are activated primarily by the Gbetagamma subunits, but a paper by Peleg et al. (2002 [this issue of Neuron]) demonstrates a role for Galpha subunits in suppressing basal activity and supports the idea of a macromolecular complex of G protein, GIRK, and perhaps RGS protein.

引用

页码：6 / 8

页数：3

共 14 条

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