Endothelial progenitor cells in chronic renal insufficiency

被引：31

作者：

Herbrig, Kay ^{[1
]}

Pistrosch, Frank ^{[1
]}

Foerster, Sarah ^{[1
]}

Gross, Peter ^{[1
]}

机构：

[1] Tech Univ Dresden, Dept Internal Med 2, Div Nephrol, D-8027 Dresden, Germany

来源：

KIDNEY & BLOOD PRESSURE RESEARCH | 2006年 / 29卷 / 01期

关键词：

endothelial progenitor cells; atherosclerosis; end-stage renal disease; chronic renal insufficiency;

D O I：

10.1159/000092484

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

There is growing evidence for a role of endothelial progenitor cells (EPCs) in the repair of damaged endothelium. It remains unclear which cell populations are most useful for clinical trials. Administration of drugs increasing EPC numbers and/or improving functional properties seems attractive. Further basic research is necessary to understand the mechanisms of mobilization, differentiation and homing of EPC in general and in particular under uremic conditions. Nephrologists should search for strategies to ameliorate EPC dysfunction of uremia. In this way it might be possible to test whether improved EPC biology is associated with decreased cardiovascular mortality in uremic humans. In any such studies the difficulties are going to be related to the complex procedures for EPC isolation, the testing of their identity and differentiation and their propagation before use. Copyright (c) 2006 S. Karger AG, Basel

引用

页码：24 / 31

页数：8

共 61 条

[1] Comparison of human skeletal myoblasts and bone marrow-derived CD133+ progenitors for the repair of infarcted myocardium [J].

Agbulut, O ;

Vandervelde, S ;

Al Attar, N ;

Larghero, J ;

Ghostine, S ;

Léobon, B ;

Robidel, E ;

Borsani, P ;

Le Lorc'h, M ;

Bissery, A ;

Chomienne, C ;

Bruneval, P ;

Marolleau, JP ;

Vilquin, JT ;

Hagège, A ;

Samuel, JL ;

Menasché, P .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 44 (02) :458-463

[2] Mobilizing endothelial progenitor cells [J].

Aicher, A ;

Zeiher, AM ;

Dimmeler, S .

HYPERTENSION, 2005, 45 (03) :321-325

[3] Isolation of putative progenitor endothelial cells for angiogenesis [J].

Asahara, T ;

Murohara, T ;

Sullivan, A ;

Silver, M ;

vanderZee, R ;

Li, T ;

Witzenbichler, B ;

Schatteman, G ;

Isner, JM .

SCIENCE, 1997, 275 (5302) :964-967

[4] Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction -: (TOPCARE-AMI) [J].

Assmus, B ;

Schächinger, V ;

Teupe, C ;

Britten, M ;

Lehmann, R ;

Döbert, N ;

Grünwald, F ;

Aicher, A ;

Urbich, C ;

Martin, H ;

Hoelzer, D ;

Dimmeler, S ;

Zeiher, AM .

CIRCULATION, 2002, 106 (24) :3009-3017

[5] Erythropoietin regulates endothelial progenitor cells [J].

Bahlmann, FH ;

de Groot, K ;

Spandau, JM ;

Landry, AL ;

Hertel, B ;

Duckett, T ;

Boehm, SM ;

Menne, J ;

Haller, H ;

Fliser, D .

BLOOD, 2004, 103 (03) :921-926

[6] Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin - Rapid communication [J].

Bahlmann, FH ;

DeGroot, K ;

Duckert, T ;

Niemczyk, E ;

Bahlmann, E ;

Boehm, SM ;

Haller, H ;

Fliser, D .

KIDNEY INTERNATIONAL, 2003, 64 (05) :1648-1652

[7]

BRICKMAN AS, 1974, ARCH INTERN MED, V134, P883

[8] Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease [J].

Chan, CT ;

Li, SH ;

Verma, S .

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2005, 289 (04) :F679-F684

[9] RETRACTED: Number and activity of endothelial progenitor cells from peripheral blood in patients with hypercholesterolaemia (Retracted Article. See vol 119, pg 545, 2010) [J].

Chen, JZ ;

Zhang, FR ;

Tao, QM ;

Wang, XX ;

Zhu, JH ;

Zhu, JH .

CLINICAL SCIENCE, 2004, 107 (03) :273-280

[10] Effects of homocysteine on number and activity of endothelial progenitor cells from peripheral blood [J].

Chen, JZ ;

Zhu, JH ;

Wang, XX ;

Zhu, JH ;

Xie, XD ;

Sun, J ;

Shang, YP ;

Guo, XG ;

Dai, HM ;

Hu, SJ .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2004, 36 (02) :233-239

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