A new miniature x-ray source for interstitial radiosurgery: Device description

被引:97
作者
Dinsmore, M
Harte, KJ
Sliski, AP
Smith, DO
Nomikos, PM
Dalterio, MJ
Boom, AJ
Leonard, WF
Oettinger, PE
Yanch, JC
机构
[1] Photoelectron Corporation, Waltham, MA 02154
[2] Department of Nuclear Engineering, Massachusetts Inst. of Technology, Cambridge
关键词
interstitial radiosurgery; stereotactic radiosurgery; x-ray source;
D O I
10.1118/1.597790
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A device that generates low-energy x rays at the tip of a needle-like probe was developed for stereotactic interstitial radiosurgery. Electrons from a small thermionic gun are accelerated to a final energy of up to 40 keV and directed along a 3 mm outside diameter drift tube to a thin Au target, where the beam size is approximately 0.3 mm. All high-voltage electronics are in the probe housing, connected by low-voltage cable to a battery-operated control box. X-ray output, which is nearly isotropic, consists of a bremsstrahlung spectrum and several lines between 7 and 14 keV, with characteristic radiation contributing 15% of the total energy output. To date, 14 patients with metastatic brain tumors have been treated with this device. (C) 1996 American Association of Physicists in Medicine.
引用
收藏
页码:45 / 52
页数:8
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