A new miniature x-ray device for interstitial radiosurgery: Dosimetry

被引：99

作者：

Beatty, J ^{[1
]}

Biggs, PJ ^{[1
]}

Gall, K ^{[1
]}

Okunieff, P ^{[1
]}

Pardo, FS ^{[1
]}

Harte, KJ ^{[1
]}

Dalterio, MJ ^{[1
]}

Sliski, AP ^{[1
]}

机构：

[1] PHOTOELECTRON CORP,WALTHAM,MA 02154

来源：

MEDICAL PHYSICS | 1996年 / 23卷 / 01期

关键词：

stereotactic radiosurgery; dosimetry; low-energy x rays;

D O I：

10.1118/1.597791

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A miniature, battery operated 40 kV x-ray device has been developed for the interstitial treatment of small tumors (<3 cm diam) in humans. X rays are emitted from the tip of a 10 cm long, 3 mm diameter probe that is stereotactically inserted into the tumor. The beam, characterized by half-value layer (HVL), spectrum analysis, and isodose contours, behaves essentially as a point isotropic source with an effective energy of 20 keV at a depth of 10 mm in water. The absolute output from the device was measured using a parallel plate ionization chamber, modified with a platinum aperture. The dose rate in water determined from these chamber measurements was found to be nominally 150 cGy/min at a distance of 10 mm for a beam current of 40 mu A and voltage of 40 kV. The dose in water falls off approximately as the third power of the distance. To date, 14 patients have been treated with this device in a phase I clinical trial. (C) 1996 American Association of Physicists in Medicine.

引用

页码：53 / 62

页数：10

共 9 条

[1]

APUZZO MLJ, 1988, STEREOTACTIC NEUROSU, V2

[2]

COSGROVE GR, IN PRESS TXB STEREOT

[3]

FLICKINGER JC, 1992, STEREOTACTIC RADIOSU, V3, P51

[4]

GALL K, 1993, MED PHYS, V20, P925