Biofilm on ventriculoperitoneal shunt tubing as a cause of treatment failure in coccidioidal meningitis

被引：55

作者：

Davis, LE

Cook, G

Costerton, JW

机构：

[1] New Mexico VA Hlth Care Syst, Albuquerque, NM 87108 USA

[2] Univ New Mexico, Sch Med, Albuquerque, NM 87131 USA

[3] Bacterin, Bozeman, MT USA

[4] Montana State Univ, Bozeman, MT 59717 USA

来源：

EMERGING INFECTIOUS DISEASES | 2002年 / 8卷 / 04期

关键词：

D O I：

10.3201/eid0804.010103

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient's taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prostheses or indwelling catheters are present.

引用

页码：376 / 379

页数：4

共 15 条

[11] COCCIDIOIDES-IMMITIS MENINGITIS WITH ARTHROCONIDIA IN CEREBROSPINAL-FLUID - REPORT OF THE 1ST CASE AND REVIEW OF THE ARTHROCONIDIA LITERATURE [J].