Heterocyclizations via TosMIC-Based Multicomponent Reactions: A New Approach to One-Pot Facile Synthesis of Substituted Quinoxaline Derivatives

被引：27

作者：

Neochoritis, Constantinos ^{[1
]}

Idou-Stephanatou, Julia Stephan ^{[1
]}

Tsoleridis, Constantinos A. ^{[1
]}

机构：

[1] Univ Thessaloniki, Organ Chem Lab, Dept Chem, Thessaloniki 54124, Macedonia, Greece

来源：

SYNLETT | 2009年 / 02期

关键词：

multicomponent reactions; TosMIC; quinoxalines; TYROSINE KINASE-ACTIVITY; ALPHA-HYDROXY KETONES; RECEPTOR ANTAGONISTS; O-PHENYLENEDIAMINES; OXIDATION PROCESSES; TANDEM OXIDATION; AMMONIUM-NITRATE; EFFICIENT; ANTIMYCOBACTERIAL; CYCLIZATION;

D O I：

10.1055/s-0028-1087518

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel multicomponent reaction involving o-phenylenediamines, aldehydes and p-toluenesulfonylmethyl isocyanide (TosMIC) in the presence of a base leading to the formation of quinoxalines in very good yields is described.

引用

页码：302 / 305

页数：4

共 54 条

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